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In any infertility textbook it is explained that one of the first, if not the first, condition to be ruled out is hypothyroidism. Low thyroid function is more than enough to explain infertility. Unfortunately, the textbooks also indicate that low thyroid function can be ruled out with thyroid blood tests. However, there are many patients with low thyroid function that have normal thyroid blood tests because they are suffering from Wilson’s Temperature Syndrome (a reversible peripheral conversion problem), not hypothyroidism (thought of as a permanent glandular problem).

For years, some Gynecologists have been giving some of their infertile patients T3, with good results, even though their thyroid tests were perfectly normal.

Thyroid blood tests can only diagnose glandular causes of low thyroid function, not peripheral causes like Wilson’s Temperature Syndrome.

Low thyroid function should be ruled out first in infertility because it is probably the easiest cause of infertility to treat. Not only is Wilsons Temperature Syndrome easy to treat, but it has the added bonus of being reversible. It can be persistently cured. People can remain improved even after the treatment’s been discontinued.

Patients with low body temperatures and low thyroid symtpoms may benefit from T3 therapy for Wilsons Temperature Syndrome and may be able to conceive when all else has failed.

About the Author:

Denis Wilson, MD described Wilson 's Temperature Syndrome in 1988 after observing people with symptoms of low thyroid and low body temperature, yet who had normal blood tests. He found that by normalizing their temperatures with T3 (without T4) their symptoms often remained improved even after the treatment was discontinued. He was the first doctor to use sustained-release T3.


  1. S'Tracy December 10, 2013 at 7:30 pm - Reply

    Hello Dr Denis,
    49 yrs old; my husband 60 and I have tried 5 yrs now to get pregnant; Many looking at our ages I can already see many pointing that my husband’s the problem; well, drs found a benign cist in my uterus, insisted on a hysterectomy; removed; yet I rejected the hysterectomy; one year later I went for my physical and drs at this clinic scolded me about my still being on my period; I questioned, yet reminded them that not even they are in not in charge of my period only GOD is; however, the new test they informed me about was showing benign cists in my ovaries now. HOPES or SOLUTIONS? Please.

    • Dr. Denis Wilson December 16, 2013 at 7:41 pm - Reply

      Hi S’Tracy. I can imagine a fertility doctor could do some testing on you and your husband and give you some ideas of the potential problems and solutions. I do know that women with low temperatures can have trouble getting pregnant. Some women with polycystic ovarian syndrome can lose their periods but it sounds like you are still having yours. Not too much more I can add right now. Good luck :)

  2. Courtney Covey March 20, 2014 at 12:10 pm - Reply

    Hello Dr. Wilson!
    I am 26 years old, pretty healthy ( no major medical issues). I recently found out that I have WTS, I have all but just a couple of the symptoms. I have been seeing a homeopathic doctor here in the state that I live in. I have been married for about a year and my husband and I are wanting to start a family. We aren’t having a lot of luck because of the lack of menstrual cycles. I have taken birth control, provera things like that will bring it on, but I don’t think I’m ovulating, could you recommend anything natural that I can take to bring on ovulation? Any suggestions or recommendations would be very helpful and much appreciated. Thank you for taking the time out of your busy day to help!!

  3. Embarrassed February 10, 2015 at 7:11 pm - Reply

    I’m 97.1 all the time, does this cause sperm mobility problems? What should I do and how long until things correct itself?
    Does your t3 medicine have negative effects on sperm while trying to get wife pregnant? ie: trying to keep things as natural as possible….

    • Dr. Denis Wilson February 15, 2015 at 4:09 pm - Reply

      I don’t know this for sure but my guess is that normal body temperatures may improve sperm motility and improve chances of fertility in men. I know for certain that normalizing low body temperatures improves fertility in women. Since T3 is already in our bodies, I do not believe that T3 taken by mouth would adversely affect sperm any more than the T3 already in our bodies. But, I do know that T3 is vital for nearly every bodily function (it tells the body how fast to transcribe DNA).

  4. Dr. Denis Wilson March 15, 2015 at 9:02 am - Reply

    Hi Krishnanunni! …. … These are some ideas of what can be done to normalize the temperature. I don’t know of a doctor in India. I would be surprised though if there is no T3-only medicine available in your country. Diet (including nutrition and herbs) and exercise can be helpful measures people can try to restore their health as mentioned in the links above. Good luck to you.

  5. Kcpd June 2, 2015 at 12:14 am - Reply

    Hello Dr. I am 28 years old male. I am suffering from auto immune hypo thyroid. My current test reports are T3 (Cerum)- 83.43, T4(Cerum)- 7.4 & TSH – 3.35. Method of testing is CLIA. At present I am taking daily 75 MCG of Eltroxine. I am trying to put some weight but after eating also too much fruits, meats etc also I am not able to gain even an ounce of mass. My height is 165 cms and weight is 56 KGS. I also do not feel energetic after sleeping for 7 hours. Iseen too many doctors for thyroid but they are telling all the reports are normal but I do not feel good. After working for some hours only I get exhausted. Please suggest me what next to do.

    • Dr. Denis Wilson June 2, 2015 at 4:16 am - Reply

      Hi Kcpd, If your body temperature is low that could explain your symptoms and difficulty. You may need to educate your doctor about T3 therapy so you can get your temperature up since Eltroxine (T4) may not do it for you. Under the Doctors tab on there is a free doctor’s manual for your doctor. Otherwise you can buy my new book, “Evidence-based Approach to Restoring Thyroid Health”

  6. Kcpd June 4, 2015 at 2:06 am - Reply

    Hi Doctor, Thanks for reply. I have had a discussion to my endocrinologist. He said to me that in India the T3 therapy is not available. One day I have checked my oral temperature thrice a day 1 st time at 3 PM it was 98.6 F and after that of 3 hrs or interval it was constant at 98.6 F. Again in the next day early morning I checked the temp was 98 F. The thermometer used was mercury analog thermometer. But after that the symptom is there of feeling tired & sleepy. Could you please so kind to suggest something which is available in India.

  7. Nuria July 21, 2015 at 9:01 am - Reply

    as acupuncturist we have many women in our practice who struggle with infertility and/or overweight. Sometimes we think it’ll better if they go to the endocrinologist, but in Spain they work really mainstream and it’s not the solution. These women have tried everything and we are quite sure your treatment-strategy could help them.
    Can you give us recommendations for doctors here in Spain??

    Thanks in advance &
    kind regards from Valencia, Spain


    • Dr. Denis Wilson July 27, 2015 at 5:41 am - Reply

      I’m sorry Nuria, I don’t know of a doctor in Spain. However, I will be happy to work for free with any doctor you know there to help him/her help your patients. Best :)

  8. AM September 2, 2015 at 8:12 pm - Reply

    Hello, after about a year of suffering from unexplained panic attacks I had labs done from a fertility obgyn showing I was hypothyroid, luteal phase defect and low t. He put me on bio identical progesterone which did stimulate my thyroid (seen via more lab work). Unfortunately my panic atacks only worsened. My body temp is always around 97 and I cannot lose weight for the life of me my current free T3 on the bio identical is 3.3. Please help

    • Dr. Denis Wilson September 6, 2015 at 9:09 pm - Reply

      Panic attacks can be due to low body temperatures. Low body temperatures can be due either to low thyroid hormone production in the thyroid gland (hypothyroidism) or poor thyroid hormone conversion (Wilson’s Temperature Syndrome). If you have normal TSH now that you’re on thyroid medicine but your temperature is still low, you might have WTS. Sometimes T4 containing medicine like Synthroid or Armour can worsen the temperature and panic attacks because T4 downregulates the deiodinase enzyme. You can check for a physician near you trained in the correction of WTS.

  9. Robin November 2, 2015 at 9:47 am - Reply

    Hello, I was recently diagnosed with WTS by a naturopathic Doctor. He gave me NatureMost Thyroid Aide. He told me that it is safe to take when pregnant, as I am currently trying to conceive. After not seeing an increase in temperature I switched to your product Thyrocare. Is this safe to take while trying to conceive and during pregnancy to maintain body temperature?
    Thank you.

    • Dr. Denis Wilson November 9, 2015 at 6:39 pm - Reply

      Your physician should answer this for you. We will be happy to discuss it with your physician for free. S/he can call 800 420 5801 to connect with us.

  10. Toig Darmaa August 9, 2016 at 9:46 am - Reply

    Hi Dr,

    I started with Hyperthyroid /Grave’s disease/ in late 2011 and had a radioactive summer 2012. Drs told me that I will be normal in 2-3 months. I am hypo now I am still having all kinds of symptoms. Every winter my thyroid level become so low TCH result shows more than 10. It is happening every year since it has become hypo. I have the swollen feet and it is getting worse and worse every year. I am trying to conceive but it is not happening. I am in California US. I told my doctor about you and your treatment but she would not know anything. I had a test for T3 but it came out normal. Is that means I do not need T3 treatment? Could you please advice anything to me? IS there a doctor you can recommend for me? `

  11. Nancy December 17, 2021 at 4:19 am - Reply

    Please everyone look up iodine protocol from Dr brownstein it will help out with every issue mentioned !! You will not be sorry

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