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Hashimoto’s Thyroiditis

Hashimoto’s Thyroiditis is an auto-immune inflammation of the thyroid gland. This means that the body can sometimes aim an immune attack, similar to the way it might fight germs or cancer, against its own thyroid gland. When that occurs, white blood cells called lymphocytes can infiltrate into the tissue of the thyroid gland. When doctors remove small amounts of thyroid tissue, either with a needle biopsy or during surgery, pathologists are able to see this infiltration, using microscopes. Blood tests can also demonstrate antibodies against the thyroid gland.

Hashimoto’s is more common in women, especially of child-bearing age. It can result in diffuse swelling of the thyroid gland. Patients may not have any thyroid function complaints at all. Sometimes patients can develop symptoms of low thyroid function, and rarely, overactive thyroid symptoms.

If patients do develop low thyroid complaints it is recommended that they receive thyroid hormone replacement. However, some patients with Hashimoto’s Thyroiditis develop classic symptoms of low thyroid function and still have normal thyroid blood tests. They are often told that since their thyroid tests are normal, they can’t benefit from thyroid treatment.

In Dr. Wilson’s experience, patients with Hashimoto’s thyroiditis and Wilson’s Temperature Syndrome respond indistinguishably from other patients suffering from Wilsons Temperature Syndrome. The Hashimoto’s patients are no more, or less likely to respond favorably to the treatment, have side effects, or to relapse once their symptoms have been corrected. In addition, doctors report that they’ve seen anti-thryoid antibody levels drop in Hashimoto’s patients treated with T3.

In other words patients with Hashimoto’s disease may have normal blood tests, low body temperatures, and classic symptoms of low thyroid function. They may be told that they’re symptoms aren’t due to low thyroid function. Yet, their symptoms may respond dramatically well to proper T3 therapy for Wilson’s Temperature Syndrome, and remain improved even after the treatment’s been discontinued, thus providing a persistent cure for their complaints.

About the Author:

Denis Wilson, MD described Wilson 's Temperature Syndrome in 1988 after observing people with symptoms of low thyroid and low body temperature, yet who had normal blood tests. He found that by normalizing their temperatures with T3 (without T4) their symptoms often remained improved even after the treatment was discontinued. He was the first doctor to use sustained-release T3.


  1. Willa deFouw June 6, 2013 at 6:42 am - Reply

    Over 30 years ago I had Hashimoto’s. I have been on Synthroid since then. 2.5 years ago my Doctor increased Synthroid from .175 to .250 but the Pharmacist made a mistake and gave me .025 which I took for 3 months. My TSH reached 35. Symptoms of course got worse, panick attacks, claustrophobia, dry skin, carpal tunnel like pain, joint pain, weight gain, etc. These symptom have plagued me intermittantly for over 15 years, but I never knew why. When the mistake was discovered I was on .250 for only about 2.5 weeks and the panic attacks and claustophobia went away. I seemed to improve for a few months. My body temperature is usually between 96.5 and 97.2.
    My Doctor is will to work with me a little to try the WTS protocol. I bought the doctors manual and have studied it quite well and I want to do the protocol. I need the information regarding how the doctor should order the prescription. I think that I will order it from Medaus. I also would like a little more info regarding stopping the T4 medication, starting the T3 and where the overlap might be. Also, will I need to go back on Thyroid medication after my body temperature is back to normal.

    • Dr. Denis Wilson June 18, 2013 at 4:15 pm - Reply

      Hi Willa, will be able to help your doctor with questions about ordering and using the T3. If your doctor has more questions he can call 800 420 5801 and we can help him there as well. Whether you need medicine after the T3 protocol depends on how much thyroid function you have left. It’s possible you still have enough thyroid function to fare well off all medicine, but then again, you might very well need some thyroid medicine for life. Your doctor can try and see how you do.

  2. candy cameron October 14, 2013 at 7:33 am - Reply

    I have had a WONDERFUL experience with Wilson’s T3 protocol. I have hashimotos and have remained on the T3 for many years. Then just recently I seem to have become allergic to the methylcellulose and the compounding pharmacies all say that it is the only fill that allows for the sustained release. Dr. Wilson do you know of any other filler that works with SR/T3 or do you know of any other optional ways to do the T3 therapy. I am such a fan of this protocol and DO NOT want to have to stop it!!! :-)

    • Dr. Denis Wilson October 16, 2013 at 7:07 am - Reply

      Hi Candy, As it turns out, when people have been on T3 a long time, many times they tolerate it more easily. It may be that time-release isn’t that crucial for you anymore.

  3. MARIANDA GEORVASSILI October 14, 2013 at 10:59 am - Reply

    ia had my thyroid removed after i suffered from hashimoto ‘ s thyroiditis for 4 years . i practically lost most of my hair and gained over 50 pounds . the doctor told me that since i had my thyroid swollen i had to remove it . i take t4 now 150 mg dosage , my hair hasn’t come back but i ‘ve started to grow hair on my neck . do i need to take t3? i would appreciate it if you emailed me back , i don’t mind if you want ot charge me since i cannot fly from Greece , i would appreciate your medical opinion

    • Dr. Denis Wilson October 16, 2013 at 9:45 am - Reply

      People on T4 that still have low temperatures may benefit from T3.

  4. MA Kerrigan November 12, 2013 at 8:20 pm - Reply

    Dr. Wilson- I am a 54 year old female-I took birth-control pills for nearly 25 years and have 3 kids- I had my last child at age 40. I have been in menopause since I’ve been 47. I was presenting with hot flashes, mental fogginess- fatigue and aching joints. I did take bio-identical hormones-sub-lingual pregnenolone & estrogen, Armour thyroid & testosterone-cream and melatonin (all based on my blood work) for 3 years to get through the symptoms. They worked very well. Then I just stopped taking them as the physician I was seeing started talking about HGH injections and I was not doing that therapy.

    I was formally diagnosed with Hashimoto’s in 2009 and have 6 nodules. My TSH last month was 2.19. It can fluctuate up to 5.50. I have chosen not to take any thyroid medicine yet hoping I could regulate it naturally.The Armour thyroid I took earlier gave me heart palps so I do not want to take it again. Also my current Endocrinologist does not prescribe it. I was vitamin D deficient (25) and take 50,000 a week – am now always around 70. I also presented with other auto-immune issues- vitiligo and asthma during this time. I have been gluten( tested neg for celiac) & -sulfide – ( and various other food additives) free for the last 3 years & notice a great improvement with the asthma (meds only as needed) and joint pain. I also found out during this time that I have MTHFR 1298, 677 and PAI -1 markers ( heterzygote for all 3) – I have osteoperosis due to D deficiency and asthma meds. Last year my Dr. noticed my parathyroid was not normal – urine tests now show it is normal. (?) If you can believe I still consider myself healthy! Currently, besides the vitamin D prescription- I am only taking Isotonix Brand liquid Multi-vitamins-B-Complex – Calcium -& OPC3. I exercise and lead a busy life-have of course gained 20lbs in the last 3 years- have an average pulse of 88-95 & I need a great deal of sleep- I am trying to create a health plan for myself and navigating through all of the information- I don’t like to take pharmaceuticals if there is a natural way. With my history am I able to try this therapy to regulate or even heal my thyroid – and if so how should I proceed? I am afraid I will make myself worse if I experiment.

    • Dr. Denis Wilson November 13, 2013 at 8:03 am - Reply

      Hi :),
      Herbs can help support normal body temperatures. T3 is sometimes necessary to restore normal body temperatures. I’d recommend you get with a doctor on our referral list to help you. Good luck :)

  5. Denise Jarratt February 2, 2014 at 11:00 pm - Reply

    I’m 52, diagnosed Hashimoto’s, Osteopenia about 7 yrs. ago. My body temperature is consistently well below 97.8 normally ranging in the low 96’s and sometimes dips to 95 if a cold-front comes through. My antibodies started at 1,880 and while they have come down, they are still above 1,000 even after being on Nature-Throid 1 grain, T-3 15 mcg., Low-Dose Naltrexone 4.5 mg., Wiley Protocol Bio-Identical Hormone Replacement Therapy, Vitamin D-3, Calcium, Magnesium all from reputable, compounded pharmacies and naturopath doctors for the past 4 years. While I’m much, much better I’m still suffering from almost all the symptoms, just not as severe as before. Fatigue, low to no initiative, muscle loss/atrophy, muscle weakness/fatigue, stiff, tight neck, dry hair/skin, brittle nails, bloated stomach, constipation, intolerance to heat/cold/weather changes etc. Any recommendations would be very grateful. No participating doctors in my area… Thank you

    • Dr. Denis Wilson February 5, 2014 at 5:27 am - Reply

      Hi Denise :)
      As you probably know, I wouldn’t expect that you will feel your best as long as your temperature is low. I also wouldn’t expect 1 grain of Nature-throid and 15mcg of T3 to normalize your temperature. I’d be happy to discuss this with your doctors for free 800 420 5801. There are also herbal supplements that help support body temperatures already in the normal range.

  6. Tim Sczesny March 2, 2014 at 2:01 pm - Reply

    I’m writing you for my wife She had half her thyroid removed about 20 years ago being on lavoxal for that period of time. I went for a refill in April and was told Phizer had a recall on that Med. Believe me our life has changed since. They replaced it with Senthroid 50 mg Then reduced to 25mg On Sept. 18th 2013 I got a call from her DR. and was told to stop everything her thyroid has become Normal???
    At present she is suffering from extreme fatigue and lost her ability to walk.Some brain fog, Or do anything. I have been her caregiver for these last 9 months. She has be hospitalized 3 times, a lumbar puncture, Bone marrow test, emg, eeg,with no results to her illness. She is a cancer survivor 2002 stroke 2003 and that left her with no problems till now. My Question is can a thyroid become normal just because her blood work is???

    • Dr. Denis Wilson March 4, 2014 at 12:18 pm - Reply

      Your question: Can a thyroid become normal just because her blood work it? My translation: Does normal blood work necessarily mean that the thyroid system is healthy?
      My answer of my translation: No, people with normal blood tests can still have low body temperatures and symptoms of low thyroid function …especially if they have been subjected to or are under some kind of physical, mental, or emotional stress.

  7. Sandra May 2, 2014 at 5:46 am - Reply

    I have been seeing a natural path that follows your protocol since Feb 2014 and have not yet lost any weight and I still feel horrible. I am also depressed and tired. I feel like I’m just wasting my money and not getting better. I’m so dispointed. I’m 28 years old and 40lbs over weight, I was a happy health women and now I just don’t feel like myself. What would my next steps be here? I can’t keep spending money seeing a natural path we hasn’t helped me feel better

    • Dr. Denis Wilson May 7, 2014 at 7:26 am - Reply

      Patients normally feel better when their temperatures are better.
      Since I can’t give you medical advice, I’d be happy to speak with your Naturopath about your case (800 420 5801) for free. You can discuss your feelings with your doctor. If you don’t work well with your doctor you can consider working with another doctor.

  8. Jan June 8, 2014 at 3:44 pm - Reply

    Hi Dr. Wilson! I heard your talk on the thyroid summit today and began searching to see if having Hashimoto’s rules out WTS. Looks like it does not. So here’s my situation, I’m 62 with total hysterectomy 10 years ago for fibroids. My weight is great and I live and eat according to organic, nutrient dense foods, good sleep, regular moderate exercise and I live in San Diego, so lots of sunshine. My free t4/t3 are in mid to upper normal range with divided doses of each during the day. I use regular generics due to cost. Total each day is 87mcg T4 and 25mcg T3. Temps are 97.7-9 upon rising and are 98.3-98.6 all day until dropping to around 98.1 at bedtime.
    My concern is that my RT3 test high at 24-26 (blood test). My tsh is .0004. I feel like my thyroid gland is most likely suppressed and not producing much,if anything due to the t4 & meds. About 4 years ago, prior to my hashis diagnosis, I went off all meds in an experiment. In 5 weeks my tsh was 90. I got back on meds and it came down. I realized then, that my thyroid was not responding with enough hormone to lower the tsh and conversion was very poor, as I had most all of the hypo symptoms. I have never tried t3 on it’s own and wonder if this is good option for me to try and reset my thyroid. My last TPO test about 4 months ago, was 153. It’s never been over 200 and been down as low as 70. I do herbs, minerals and vitamins to support the thyroid and gut, as well.

    I don’t have a dr that understands or is interested in any of this. So I am my own experiment. I do get my prescriptions from a cooperative PCP who trusts me and I am grateful for that. I would appreciate any comments/suggestions you might have for me. Thank you.

    • Dr. Denis Wilson June 11, 2014 at 12:46 pm - Reply

      Hi Jan :)
      Unfortunately, I cannot give medical advice over the internet, but if your doctor calls 800 420 5801 we can set a time to discuss your case for free. T4 can downregulate the deiodinase enzyme which can explain why people can have low tsh and still have low temps and symptoms. Best regards :)

  9. Linda Valenza July 17, 2014 at 6:48 pm - Reply

    I have hash. On Naturthyoid. Have burning vagaina/burning itchy peeling heels/now getting hives or welts. Low body temp. What do you think?

    • Dr. Denis Wilson July 20, 2014 at 5:35 pm - Reply

      Low temperatures can possibly account for your symptoms. If your temperatures are low on Naturethroid you may not be converting it or utilizing it well.

  10. Kristin July 22, 2014 at 1:26 am - Reply

    I have Hashimoto’s and have always done well on Naturethroid but this year I started gaining 1 pound a week and I am cold often and my temp is low, my TSH went from 0.01 (suppressed where I wanted it) to 1.1. My labs appear to be in an optimal range and I am on a grain free & gliadin free diet. I didn’t get my RT3 back yet maybe that will reveal more.

  11. Colleen McLennan July 23, 2014 at 9:37 pm - Reply

    My naturopath took my ear temperatures and the left side did not register at first then read 91 degrees and the right read 94 the differential she suspected was caused by heat from the ear ache that I was complaining of in the right ear. She appeared disconcerted. I was not feeling chilly. I had been diagnosed with Hashimoto’s thyroiditis but the endocrinologist felt I was euthyroid but with very labile reaction (my levels appear to vacillate between hypo- and hyper- thyroid and I really don’t notice the difference) to the Synthroid (100mcg) and Liothyronine(25 mcg) that I take daily. I seldom feel cold except when I am getting sick (rarely). When originally suspected that fatigue and hair loss might be thyroid related the anti thyroid peroxidaze test result was 1080 . That test has not been repeated that I know of. The naturopath thinks adrenal exhaustion and possible auto immune difficulties are likely imbalances. This has been a stressful period, I have been primary caregiver to my husband following a debilitating stroke which left him bed ridden, and he died last month after 7 months at home. What should I do to pursue wellness and address my symptoms…my new GP is not very familiar with me and I do not think any medical practitioner has taken my temp in a long time. Do I need to follow this up.

  12. Yael August 20, 2014 at 9:26 am - Reply

    Hi Dr. Wilson
    I am 19 yrs old and was diagnosed with hypothyroidism/Hashimoto’s thyroiditis 4 years ago. I am on 50/75 mcg of synthroid and 2.5 mcg of cytomel.At first, I was only on synthroid but after 2 years when I didn’t see much of a difference I asked my Dr. to put me T3. I started with 5 mcg but then had problems falling asleep so was told to take only half every morning. Ever since I can remember, I have always been very cold. In the summer I would walk around with a sweater. Even at home where it’s usually 72 F I am bundled up. I still have many symptoms, too, like: PMS, low body temperature, low heart rate, low blood pressure, hair loss, anxiety, fatigue. I also possibly have Irritable bowel syndrome. And starting with T3 did not change anything. Is there any other reason this could be? Also, my recent TSH about a month ago was .17, and the Dr. said it was low because of the T3. What do you think??
    Thank you very much

    • Dr. Denis Wilson August 24, 2014 at 9:18 pm - Reply

      T3 and T4 can lower the TSH, for sure.
      Low body temperatures can explain your symptoms.
      Temperatures can be normalized by correctly adjusting the thyroid hormones, but adding a little T3 might not have been the adjustment needed to normalize your temperature, and we wouldn’t expect your symptoms to improve until your temperature is normalized.

  13. Laura August 27, 2014 at 2:47 pm - Reply

    Hi Dr. Wilson,

    Could perimenopausal women who are hot flashing and having weight fluctuations benefit from a low dose of T3? Thanks for your contribution to medicine. Your wisdom has really helped some of my patients!

    • Dr. Denis Wilson September 14, 2014 at 8:29 pm - Reply

      Yes, they might if they have low body temperatures. I’m a big proponent of normalizing low body temperatures to see what symptoms improve.

  14. Jaron du Preez September 22, 2014 at 9:24 am - Reply

    I have been diagnosed with Graves disease (hyperthyroidism). My T3 and T4 levels are very high and my TSH is very low. I doesn’t sound as if the WTS technique will help for my condition? Am I correct?

    • Dr. Denis Wilson September 24, 2014 at 5:34 am - Reply

      T3 is not the usual treatment for Graves. However, some people with Graves can still have low body temperature and may have WTS as well. Normally, the approach would be to treat the Graves first, and then correct the WTS if it remains.

  15. Amanda King October 1, 2014 at 8:25 am - Reply

    Please help -can I discontinue my Thyroxine T4 and take T3 dessicated only

    • Dr. Denis Wilson October 5, 2014 at 5:53 am - Reply

      I can’t give medical advice over the internet but I’d be happy to discuss your case for free with your doctor (doctor can call 800 420 5801 to make arrangements)

  16. Mike October 15, 2014 at 1:39 pm - Reply

    Hi Dr. Wilson,
    I’m a 50 yr old male weighing 135 lbs that was diag with Hashi’s over 10+ years ago with high antibodies and tsh. I never began any treatment thinking I would try everything naturally to restore my thyroid. After all these years, I’ve done a lot of things right (remove silver fillings, chlorine filters, fluoride free, gluten free diet, etc… but just can’t get things working! I have a low basal morn temp around 72.2 and pulse of 52. I’m really hesitant on starting any medicine for the rest of my life. Would it make sense for someone in my shoes to try this temporary protocol of T3 only before I give in to taking a compounded / synthetic Rx?
    Thanks & God Bless!

    • Dr. Denis Wilson October 19, 2014 at 8:59 pm - Reply

      Hi Mike :)
      Sounds like you’ve made some good changes over the years. People with Hashimoto’s often benefit from herbal and T3 only treatment. Sometimes, they do now need medicine for life. I recommend you consult with a doctor on our list to help you address your concerns. Best :)

  17. Mike November 14, 2014 at 5:45 am - Reply

    Hi again Dr Wilson!
    I have been trying to learn more on your site & introduce your protocol to my Doctor since she’s very open minded and would be a good fit with your practice… When you describe a Hashi patient as having “normal thyroid blood tests” are you just referring to T3 & T4 levels only and not including high TSH & Antibodies? Like in my case, I have had high TSH levels in 6-8 range & TPO levels in the 600-700 range but normal T3 & T4 levels. In addition I have low temps & many classic symptoms.
    Thanks again for your work!

  18. Brenda Harper March 21, 2015 at 1:23 pm - Reply

    Dr. Wilson,

    I am 58 with Hashimote’s, Lupus, Loss of Chemical tolerance, Chronic Inflammatory Response syndrome, and victims of mold and Levaquine toxicity. After mold and Levaquine my temp dropped to 94.6-95.6 range, and has stayed there since 2008 unless brought up by artificial means. I finally talked my doctor into allowing me to try your protocol. After reading your book I also added Iodine, (also I am a downwinder from childhood). I have already lost uterus, ovaries and breast to overwhelming cysts. Boy to I wish I had found this info years ago, I think iodine might have saved my female organs. Anyway the protocol worked well. My temp came up to 97.2-6 mornings up to 98.2-6 by evening. I took going up to 40 mcg t3 morning and night. I feel somewhat better. You can see a visible change in my finger nails, eyebrows have some regrowth and hair growing better. Brain fog improved energy still low but improved. I just did testing I was on 25 mcg morning at night the day of test and I did not take meds before testing as instructed. free t4 a little low, free t3 okay, antibodies went from 518 to 538 not a significant change but TSH went from 4 to over 12. And my testosterone jumped high when it has been low for some time. My doctor is freaking out, afraid the one nodual which has been biopsied 2 times and found nothing will become cancerous. I did go back on genetic synthroid as none of the naturals have worked for me before. And I am still on 5 mcg time release t3 morning and night exact same time. She wants me to stop iodine as well. I had got up to 100. I have dropped back to 25 but really concerned about going off of it. I am wondering if the increase T3 or Iodine could cause the change in TSH and testosterone and if it is a temporary thing. Since I feel better and nails show a clear line of improvement my thumbs even getting back small light half moons. They still have a lot of vertical ridges but the top layer of nail is no longer flaking off. Temperature seems to be holding, blood pressure is 90’/50’s up from 70’s/40’s Pulse up to 70 from 45. Weight despite good diet is actually up a couple pounds. I assume in time that will also stabilize. My doctor says with TSH that high it is not a surprise. Is this TSH a normal thing that will stabilize. I have had hashi for 20 years maybe longer. I did go back on generic synthroid 50 mcg morning and night with the T3. I also take the co-factors. You do not have any doctors on your list near me in Boise Idaho.

    • Dr. Denis Wilson March 22, 2015 at 2:38 am - Reply

      I will be happy to discuss your case for free with your doctor who can call 800 420 5801 to make arrangements. TSH can go up when people take extra iodine. This effect is usually temporary and can normalize in 6-9 months even with the patient continuing to take iodine. High TSH can also be a sign of inadequate hormone replacement. So I’d be happy to discuss with your doctor to give ideas on how to sort it out.

  19. Dakota April 13, 2015 at 9:53 pm - Reply

    Hello, I have so many of hypothyroidism symptoms. I have a positive thyroglobulin antibodies test but the rest of my tests are normal. My test say I have 12 high out of range for my antibodies. However, Doctors feel it is not enough to say I have anything at all. I also found out about hypothyroidism leading to low temps. My resting temp is around 96.3 and when I feel like I am burning up 97.5. I feel like every day life is such a struggle and no one will help me. This website makes me question and wonder if maybe it is possible that I may have Wilson’s Temperature Syndrome.

    • Dr. Denis Wilson April 19, 2015 at 8:08 am - Reply

      I’d say it’s definitely possible, because what you’re describing is classic for WTS.

  20. Jess April 27, 2015 at 12:30 pm - Reply

    Hi, I have Hashimotos and my doctor put me on the WTS protocol. I was doing good once I hit 30mg and my temp went up to 98.2 and my low BS, nightsweats, and the strong ammonia smell in my urine disappeared. But as I increased the dosage my temp started to drop and my sx returned. I am now at 75mg and my temp is at 97.2. I don’t understand what’s happening. I figured I would have captured my temp by now. I’m guessing I should continue to 90mg. Is it possible that my body is already compensating even though I never reached 98.6? Thanks!!

  21. Hanne P May 1, 2015 at 12:58 am - Reply

    Hi. I am form Denmark and new here, I just learned about this syndrome. I have Hashimotos, but my endochrinologist only adressed my low thyroid, he would not talk about the TPO result from the hospital or the Reverse T3 (557) from a private doctor, and now he stopped me “because he does’nt treat chronic sickness”. Because I read about this syndrome 3 weeks ago, I stopped my Euthyrox (T4) 50 microg. immediately and only took 1 tablet of 5 microgr. Liothyronin (T3) in the evening, and half a tablet in the morning. Already next day I felt a small tremble, which I liked, because I thougt that: Now something is happening! And the next day again my husband looked at me and said: You seem to have more energy!!! BUT, after two weeks I am fatigued again, and afraid that I am playing with my health, dealing with my medicine on my own. So my question to you is: Can I go on only using the Liothyronin, and with only my GP helping me, which numbers should my free T3 be within? Hope som much for an answer, thank you.

    • Dr. Denis Wilson May 3, 2015 at 7:15 pm - Reply

      Hi Hanne :)
      General Practitioners are licensed to prescribe thyroid medicine, yes. We can discuss your case with your GP to help him/her understand treatment and management options. The T3 therapy is not managed according to blood tests alone. Blood tests help with diagnosis but the goal of T3 therapy, when needed, is to normalize the body temperature. Your GP can call 802 262 6100 USA to make arrangements so that we can discuss your case for free.
      Best :)

  22. marie May 15, 2015 at 5:39 am - Reply

    Hi Dr. Wilson. I have Hashimotos, Chronic Fatigue, sluggish Liver, Oral Ph 6.2, Gluten allergy. This is the short list. I usually have low temp and fit the profile of Wilson temperature syndrome. I am going to see a new Endocrinologist next week. What test would you recommend.
    Thank you

    • Dr. Denis Wilson May 17, 2015 at 7:46 pm - Reply

      Number 1, I’d recommend that you check your body temperature. Number 2, TSH to rule out hypothyroidism. All of your tests may be completely normal, but a low temperature could still explain your symptoms.

  23. Adonis May 27, 2015 at 10:24 pm - Reply

    I believe 3 years ago I started experiencing many under active thyroid symptoms such as chronic muscle pain and stiff joints, muscle spasms, cold and heat intolerance, vision problems, weight gain of 20 pounds, memory problems, enlarged goiter with nodule and a positive THyroid peroxidase antibody and borderline .09 T4 and all other test are normal. I’m diagnosed with Fibromyalgia and peripheral neuropathy. I now have muscle wasting several spots on my legs, difficulty swallowing, sweating and shortness of breath. My Endocrinologist said I have Hashimoto’s, but I don’t need treatment. My question is, is it possible, albeit rare, that my Hashimoto’s could be the cause of my muscle wasting, dysphagia, and shortness of breath?? No other test has explained this.

    Thank you,


    • Dr. Denis Wilson June 2, 2015 at 5:05 am - Reply

      Hi Adonis,
      Yes, I do believe that low temperatures could explain at least part of your symptoms. People with low temps can have trouble swallowing, exercising, and breathing. Of course, other things could cause that also such as multiple sclerosis or amyotropic lateral sclerosis.

  24. Cheryl June 18, 2015 at 7:42 am - Reply

    Hi Dr. Wilson, I have chronic Lyme disease which caused Hashimoto’s. Currently, my antibodies are within normal limits. I am on 50mcg bio-identical (time released) T3 per day. My TSH, T3, T4, RT3 are all currently within normal limits. I am still having problems with wt. gain despite not eating much (under 2000 cal/day). I have an average body temperature of 97.3 but at times go as low as 95.3, etc. My temperature increased about 0.3 degrees after starting on the T3. Is there something else that can be causing this low temperature? Is there any other way to increase temperature besides T3? Is there a maximum amount of T3 that can be used? My doctor says I’m on the max now. Please advise.

  25. Robert M July 5, 2015 at 11:59 am - Reply

    Hello Dr Wilson, I heard your seminar on the thyroid summit with Susie Cohen and Amy meyers. I am a
    CNC and naturopath. I have been diagnosed with hoshimotos from blood test. I have read by some
    doctors that if you cant tolerate armour or nature throid, which I can’t, that we should use a t3-t4 combo.
    my body temp is hanging around 96 (basil). I know I need to find a Dr who can write the scripts, but is there a basic protocol to start with. I will go back and listen to your summit tape and see if it is on there but I think you were talking mainly about the full t3, but you stated that its not a good fit for those with heart disease, and every time I try to use thyroid hormone, my heart goes into palpitations and pain. but i’ve never tried the t3 or t4 before.

  26. Robert M July 14, 2015 at 9:17 pm - Reply

    that was a good story about your secretary, you tested the T3 first time…LOL…ok I get what U R saying but it sounds like U R only concerned about mouth temp of 98.6 I always thought the basil under arm was more important..? so I tried the upgraded MCT oil, it brought my (mouth) body temp up to 98.6 for (in 2 days) 1st time in prolly 20 yrs. and you are right it makes your brain become very focused and energy off the charts. (this is a 6x concentrate of coconut oil) (brain octane is 18x concentrate) but yet my basil U A temp is still 96.
    but weird thing is if I use regular coconut oil I get chest pains.( I suspect it is bringing metabolism up like armour thyroid) so in your experience does the WT3 have any effect on UA basil temp or just the mouth, and do you think it even matters about the UA basil temp…? thanks for being here and best.RM

  27. amber August 18, 2015 at 12:07 pm - Reply

    My regular MD diagnosed me with Hypothyroidism about years back and I was placed on Levothyroxine. I had test done and am back normal. Last month my dr. Ordered my blood work and also tested the antibodies and test 165 and diagnosed me with Hashimoto. Well I just went to the Endocrine Dr and he told me that I have Hashimoto but since my other levels tested fine that I don’t have a thyroid problem. HELP ME! then why do I feel so tired, no energy, dizzy, weight gain??? I don’t think this Endrconoligist knows what he’s talking about. He said none of my symptoms are from the thyroid at all.

    • Dr. Denis Wilson August 20, 2015 at 8:39 am - Reply

      Judging your metabolic rate from the blood tests instead of the temperature is like trying to determine how fast your car is traveling by looking at the gas gauge instead of the speedometer. If your temperature is low, that could certainly explain many of your symptoms.

  28. Fay September 16, 2015 at 3:39 am - Reply

    help I’ve tried it all T4, T3/T4, armour, armour/T3, thyroid gold, thyroid gold/T3 – I’m sure I don’t convert my latest bloods show TSH 0.02 which never alters, T3 is elevated T4 is fine would I get on better with T3 only? I have hashimotos which was left undiagnosed for 20 years due to normal thyroid tests

    • Dr. Denis Wilson September 20, 2015 at 8:26 pm - Reply

      If your body temperature is low then you might benefit from normalizing your body temperature with diet, lifestyle, and/or T3 therapy.

  29. Antoinette October 3, 2015 at 10:19 am - Reply

    Hi Dr. Wilson,

    I just stumbled upon your website! I have Hashimotos/hypo and just wanted to know your opinion on iodine, I have read that it is dangerous for people with hashi’s and I have also read the exact opposite.

    Thank You,

    • Dr. Denis Wilson October 5, 2015 at 9:35 am - Reply

      Hi Annie :) We normally recommend iodine in the management of Hashi’s. It’s true that the rare patient may continue to have ups and downs with their Hashimoto’s while on iodine, most Hashi patients benefit from it, I feel. We normally include selenium and herbs and zinc with the iodine.

  30. Josie October 6, 2015 at 2:52 pm - Reply

    Hi Dr. Wilson,
    I have had hypo symptoms for years and consistently low body temps (usually 97 range). I believe that my issue is partly adrenal, but I also know I have an issue converting t4 to t3. Would love to get to the bottom of that. My labs consistently come back with a low TSH, normal FT4, borderline normal FT3. I have been told that my FT3 should be in the upper fourth of the range to feel optimal. My question is: how does the thyroid reset itself with a temporary T3 protocol and not revert back when you discontinue? I don’t know if there’s an area on the site that you explain this or you have a quick explanation. Thanks

    • Dr. Denis Wilson October 15, 2015 at 3:14 pm - Reply

      Yes Josie, T3 therapy is usually short-term, on the order of months. The idea is to normalize the body temperature with the T3 and then gradually wean off the T3 so that the body can then hopefully maintain the restored normal body temperature on its own.

  31. Jennifer October 19, 2015 at 3:18 pm - Reply

    I have been diagnosed with hashimotos. Normal range 0-99, and mine was 513. My tsh is always very low .49 (sometimes lower), Ft4 .97 , ft3 3.06, Rt3 23.
    I am currently not being treated for my thyroid at all. I have gained 45 lbs, sleep all the time, cannot remember anything, freezing hands and feet with swings of heat intolerance and horrible swelling. My skin looks like leather. And the list goes on and on. I discovered in research that my ratio of ft3/Rt3 when caliberated is 14.5, my understanding is that normal function should be 20 and above. I expierence symptoms of both hypo and hyper. Would I benefit from a t3 treatment?

    • Dr. Denis Wilson November 10, 2015 at 4:22 pm - Reply

      Hashimoto’s patients with low temperatures often benefit from normalizing their low body temperatures with T3-only therapy.

  32. Michelle October 29, 2015 at 8:26 am - Reply

    Hello Dr. Wilson,

    My daughter is 19 and she was diagnosed at age 17 with Hashimotos. She has been on synthroid ever since and they keep up’ing her dose each time we go back in because her levels are not improving. Her symptoms are getting worse. She is 19 and all she wants to do is sleep. It is effecting her quality of life. She is always cold, complains of body aches, headaches, and more. She is getting depressed. She doesn’t think that the synthroid is helpful so she doesn’t want to take it. She has an appointment tomorrow with the endocrinologist. I want to see about having her started on T3 do you think this might be beneficial to her? What questions should we be asking? Should I ask for additional testing?

    • Dr. Denis Wilson November 10, 2015 at 5:21 am - Reply

      Hi Michelle, the purpose of the thyroid system is to provide a normal metabolic rate, which is measured by body temperature. As long as the temperature is not normal we can’t expect your daughter to feel better. T4 and RT3 can downregulate the deiodinase enzyme. My book, “Evidence-based approach to restoring thyroid health” explains all about it. It has hundreds of scientific references. Your doctor could read that or I would be happy to discuss your case with your doctor for free.

  33. Shanna November 5, 2015 at 11:25 am - Reply

    Hi Dr. Wilson,

    I came across this article after months of research, I am not sure how I missed this before! Brilliant! Over the past 3 years I have been living in a constant fog, having difficulty concentrating and writing (I am a marketing professional). My skin is incredibly dry and I am losing my hair as well. Over the last year symptoms have gotten worse. Its difficult to not become depressed (but I am one to shake it off and continue trying to be myself as much as I can). My weight has steadily increased over the last year with high protein low carb diet and exercise. I cut out carbs completely just to maintain my weight. I have seen various doctors, my labs have always come back in normal ranges. My symptoms are only getting worse. I am not sure what is going on. Recently I learned about Hashimotos and was considering having tests run on this, however I am not exactly sure if I should as my doctors say my thyroid is fine (and I feel like I am just going crazy). Recent blood work is:
    TSH:1.100 uIU/mL Range:0.450 – 4.500
    Free T4: 1.40 ng/dL Range: 0.82 – 1.77
    T3: 138 ng/dL Range: 71 – 180

    I have never had free T3 or antibodies run. Doctor said it was unnecessary. Should I ask my doctor to run these, or would my normal levels indicate these test are not needed? I am also confused with all the ideal ranges out there, as well as knowing/understanding whether I fall within optimal ranges. If I am not in optimal ranges, I would seek a doctor in Houston with that mentality (unfortunately many do not accept insurance now and wanting advice prior to making that call).


    Dazed and confused in Houston, seeking a professional opinion

  34. Robert December 2, 2015 at 6:18 am - Reply

    Hi Dr. Wilson my wife has been on 50 -75 mcgs of T3 and 1 grain of Naturethyroid a day and feels great , but her doctor said its not good to stay on T3 forever and lowered T3 and added another grain of Naturethyroid .
    Now she feels worse and is having heart paps
    So my question to you is it dangerous to be on mostly T3 for life she does have hashis that went untreated for many many years

    • Dr. Denis Wilson December 5, 2015 at 5:41 pm - Reply

      Many physicians feel that it is fine for patients to be on mostly T3 for years. Medical followup is appropriate for any medications given long term.

  35. Lori December 12, 2015 at 5:00 pm - Reply

    Hi, I have had very low temp (averaging 96.6 at mid-day and as low as 95.3 early in the morning) along with joint pain, constipation, no period for months on end (despite being 34 years old), brain fog, weight gain of more 10% of my normal weight (was 143, now 160), problems sleeping, cold extremities and dry skin…all in the past 1.5 years. I’ve been to endocrinologists, gynocologists, gastroenterologists and immunologists and no one can figure it out. I’ve done dozens of blood tests, CT scans, ultrasounds, urine tests, you name it– and whatever is wrong can’t be measured. I currently take NatureThroid (97.5 grams). It’s a combination of T3 and T4 like Armour. My endocrinologist might be willing to try me just on T3 but she is a traditional doctor so I’m not sure she’ll believe in Wilson’s. There doesn’t appear to be one of the doctors in this network where I live. Is there a prescription T3 drug I should request from her to try or do I need to go through a compound pharmacy?

    • Dr. Denis Wilson December 14, 2015 at 3:03 pm - Reply

      I would recommend your doctor to contact and ask them about Sustained-release T3. It is usually much better tolerated than instant-release Cytomel.

  36. Michaela Johnson December 20, 2015 at 8:24 am - Reply

    So many of these stories sound like mine. Mostly I am just exhausted with the moving target. I was originally dxd with Hashimotos when I was 21, but didn’t much consider any symptoms until I was 29 and unable to conceive, a new doctor ran bloodwork and found TSH high, I was placed on Levothyroxine and was pregnant within 3 months. Adjusted during pregnancy from 75mcg to 100mcg, horrifically taken off entirely after pregnancy when thyroid dump occurred (my new OB GYN was clueless) and then placed back on with a TSH of 35 a few months post natal. Since then there have been periods (usually lasting 3-6 months) of “normal levels” and smaller periods within that where I feel symptom free. I began taking my temperature per your recording sheet and am consistently seeing 95.3-97.1 (as a high in the early am before getting up). My temp was cause for alarm because I noticed while checking my sons (who is now four) as part of “mommy check yours too” that I was very low every time. I’ve also had chronically low BP which docs always attributed to the fact I hike a few miles multiple times a week- but I believe is Hashi at its finest. I will be looking for a doctor on your list and am hopeful I can finally manage the madness. I wasn’t sure initially that someone with Hashi could also benefit from WT3, but it sounds like I can. I am incredibly organic (garden and chickens of my own) and am dairy free. I live a busy (business owner, entrepreneur), active lifestyle and am looking forward to removing this ongoing piece of stress from my life.

    • Dr. Denis Wilson December 20, 2015 at 3:27 pm - Reply

      Yes, definitely, people with Hashimoto’s can also improve their body temperatures. Good luck :)

  37. Lin December 25, 2015 at 7:07 pm - Reply

    Thank you for your work, Dr. Wilson! I have recently been enlightened into how all of this thyroid stuff works. My Dr is willing to prescribe t3 only to me for a while, which is what we both believe that I need. However, my question for you is if you have ever prescribed it to nursing Mothers. I am concerned about what it might do to my daughter’s thyroid as she gets a little bit of it through my milk. I know there haven’t been many studies on this, so I thought I’d ask if you had any experience. Thank you so much!

    • Dr. Denis Wilson December 29, 2015 at 7:30 pm - Reply

      Hi Lin :) Since T3 does pass into the breast milk I have not prescribed it to nursing mothers. I recommend that they postpone treatment or stop nursing. It’s a judgement call as to which is most important right now.

  38. Karen McAuliffe January 10, 2016 at 3:02 pm - Reply

    Hello Dr. Wilson,

    I’d very much appreciate it if you could give me a little advice on the following issue (as you seem to be the expert!). I was diagnosed with fibromyalgia in 2011. About 22 months ago, I experienced every type of hypothyroid symptom possible (lost my hair, hair went from curly to straight, gained 10 lbs that wouldn’t budge with exercise/dieting, no libido, carpel tunnel, and the worst- MAJOR cognition issues).
    I was tested and the results were normal. However, 18 mos later, I was retested for BOTH T4 and T3 instead of just the former as was previously done. My diagnostician (had to finally resort to one) has been treating me with Thyroxal, but it’s only been 7 weeks. I haven’t felt any better and my T3 went down 7 more “points” since I started the Thyroxal. I speak with the doc on Wed, but would like your opinion on possible next steps.
    Of note: my RBC and protein were both low when initially tested, but I haven’t yet been re-tested for those. I am gluten-sensitive,and just learned that 2 yeas ago,my gastro did NOT test me for Celiac as I had instructed her to do during a colonoscopy. I only recently learned that a biopsy needs to be done on the upper intestine, not lower. I inquired about all this due to my low T3, protein, and RBC. I have also been losing weight, primarily muscle- which I had a lot of, over the last 4 months. My appetite isn’t great but I love food so I still eat more than enough. Lastly, my older sister had a innocuous tumor on her pituitary gland that was shrunk with meds over time. Should I get a scan of my pituitary? Please help.

    • Dr. Denis Wilson January 17, 2016 at 4:07 pm - Reply

      Low temperatures can contribute to symptoms of fibromyalgia. If your body temperature is low, then by definition, your metabolic rate is low….now matter what your tests say. Next steps would include getting your body temperature. You could always get your pituitary scanned but if your thyroid tests are normal and your temperature is low then you might have a problem converting T4 to T3. I can discuss your case for free with your doctors or you can go to and look for a doctor near you.

  39. Kim February 13, 2016 at 9:09 am - Reply

    I have been having all the symptoms of hypothyroidism, sometimes my blood tests are normal and sometimes low. We moved and went to new doctor and I asked him to check for thyroid antibodies but he only checked tsh levels which came back normal. There is a family history of hypothyroidism. Should I go to new dr? Can I still have Hashimoto’s disease with my fluctuating TSH levels?

    • Dr. Denis Wilson February 21, 2016 at 1:33 pm - Reply

      Sure, you can have normal TSH, low body temperatures and hypothyroid symptoms. Most often this is due to WTS. I don’t know if you need to see another doctor but it would be good to know if your TPO antibodies are high, which would indicate that you do have Hashimoto’s as well.

  40. Sophia February 19, 2016 at 5:04 pm - Reply


    I am a nurse practitioner. I was diagnosed with HT at the age of 26 in 2013. I have always been the atypical patient who is petitie, and had fatigue and numbness and tingling. SYnthroid alone did not help with my symptoms. I then started compounding T3 and T4. Immediately my symptoms have slightly improved. However, my cholesterol is very high with a High LDL and HDL. I have been tested for familial hypercholesteremia, which was negative. I am 100 lbs, gluten and dairy free.
    In addition I have a very high heart rate ever since being on meds, even with just solely T4. mY TSH levels are within range although my antibodies are still elevated. despite lowering my thyroid hormone replacement, my heart rate is still fast, requiring me to go on a beta blocker.

    I saw a naturopath that has recommended your protocol. Have you seen patients reverse their high cholesterol and even high heart rate with this protocol. I have even tried liquid T4,T3 and my heart palpitations are still present.
    The naturopath said my Temperature was 97.8 , which is low. What is your experience with patients in my scenario.

    Thank you

    • Dr. Denis Wilson February 21, 2016 at 1:15 pm - Reply

      Absolutely, normalizing low body temperatures can have a huge and very rapid impact on lowering cholesterol levels.

  41. Shana March 3, 2016 at 5:08 pm - Reply

    Hello, I’ve had all the symptoms of Hashimoto for 8 years , a goiter , dry skin, extreme weight gain, anxiety, night vision problems, scarring alopecia, heavy menstrual, and vision issues, I’ve had several blood test they always come back normal tsh with low iron, low vitamin d , high hdl, and extremely insulin resistance . After complaining for years and having a panic attack in my doctors office they put me on synthroid .50mcg . And I feel better within 4 days! Can it be that I actually have hashimotos and normal blood work! I’m convinced I do ! My mother wasn’t diagnosed with Graves’ disease for 11 years , her blood work always came back normal until it turned into graves . I’m so afraid to lose my thyroid I’m 32 and I want to have children some day. Please help

    • Dr. Denis Wilson April 10, 2016 at 5:28 pm - Reply

      When people have no thyroid antibodies and normal TSH and low body temperatures, I would normally diagnose them as having Wilson’s Temperatures SYndromre before diagnosing them as having Hashimoto’s. Synthroid can help WTS at first, usually 2-3 months, before the person starts feeling badly again (the WTS catching up with them). If you find that your symptoms start coming back then you might be better off with T3 therapy for WTS. Good luck.

  42. CATRYNA WHITE March 24, 2016 at 6:23 am - Reply

    I am 66 years old and was diagnosed with Hyperthyroidism over 10 years ago. I firmly believe that I have had this problem since my mid/late teens. A doctor, 10 years ago prescribed Armours (25 mg per day); within 10 days I began to have heart palpitations, hives and calf pain. The Armours was stopped and a T4 substituted. I took that for 6 weeks and almost the entire time I had migraines, calf pain and suicidal thoughts. Five years ago I was diagnosed with Hashimotos and most recently, 2015, I was again put on a compounded formula of T4 and after 4 months began to have terrible anxiety attacks, within an hour, after taking it. I have taken certain ones of your supplements for the past 10 years (Thyrocare and Adaptogen). These two supplements along with other supplements and a gluten free diet have helped a great deal. Also, I was wondering if you have researched Hashimoto’s sufferers and the use of Iodine after consuming Selenium? I understand that those with Hashimotos need to have sufficient amounts of Selenium in their system before introducing Iodine.

    I have wanted, for a long time, to try your T3 protocol and am hoping to speak to my doctor about it at my next visit this coming June.

    • Dr. Denis Wilson April 10, 2016 at 3:28 pm - Reply

      Yes, I do feel that it is wise to give Selenium whenever giving Iodine and vice versa. They go very well together.

  43. D Rice May 10, 2016 at 5:46 am - Reply

    I was just recently diagnosed with Hashimoto’s Disease at the age of 46, but believe it’s probably been there for a while. I’ve complained of fatigue, muscle and joint pain, heavy periods, weight gain, insomnia, chest pain, and multiple other problems for several years, but doctors only checked my TSH and said everything was normal. Finally I had a doctor check my thyroid antibody which revealed an abnormal result along with an elevated ANA. She also ordered a thyroid ultrasound, which revealed a small (1.2cm) nodule. She sent me to an endocrinologist, who basically just blew me off and actually said that i just needed to embrace getting older! She refused to do anything because the TSH was normal, and just told me to come back in 6 months. I can assure you I will never go back to see her. I’m seeing a rheumatologist next week, but am considering seeing an immunologist if I can find one that specializes in autoimmune disorders. But in the meantime, I’m doing some research on natural or alternative therapies, and have found conflicting information on dietary restrictions. Do you have a recommendation on things to eat or avoid when dealing with Hashimoto’s? I will definitely print this article and take it with me to my next visit, whichever doctor it may be.

    • Dr. Denis Wilson May 18, 2016 at 4:15 pm - Reply

      I have seen the conflicting information you mention. I do believe that a gluten-free diet can be very helpful in some patients. Many doctors I know have told me they have seen that make a significant difference in their patients. Good luck :)

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