Hypothyroidism is due to the inadequate production of thyroid hormones by the thyroid gland. The thyroid gland is a butterfly-shaped gland just under the skin on the front of the neck. Ususally, the gland is difficult, if not impossible, to feel with the hands even by trained physicians.

Thyroid hormones play a crucial role in maintaining the correct metabolic rate. If the thyroid gland doesn’t produce and secrete enough thyroid hormone into the blood stream then the metabolism will become too slow, causing the body temperature to drop and leading to classic symptoms. These symptoms include headaches, migraines, depression, easy weight gain, fluid retention, irritability, dry skin, dry hair, panic attacks, PMS, itchiness, hair loss, allergies, and many others.

Hypothyroidism is easy to diagnose. Since the purpose of the thyroid gland is to put thyroid hormones into the blood stream, thyroid blood tests can easily measure thyroid gland function. However, there are some people who have normal thyroid blood tests that still have low body temperatures and low temperature symptoms (same symptoms of hypothyroidism). Their thyroid tests are normal but their metabolisms are still slow.

This is possible because it’s not enough for the thyroid hormone, T4 to be secreted into the blood stream by the thyroid gland, it must also be activated into T3 in the tissues. T3 is the active thyroid hormone. It is 4 times more potent than T4 and 80% of it is produced in the tissues of the body (after T4 leaves the blood stream). Wilson’s Temperature Syndrome is when people have adequate levels of thyroid hormones in the blood stream, but are still suffering from slow metabolisms. This is most likely due to an impairment in the conversion of T4 to T3 in the tissues.

Thus, hypothyroidism is a problem with the thyroid gland not putting enough thyroid hormone into the blood stream, and Wilson’s Temperature Syndrome is a problem with the tissues not properly processing the thyroid hormone that comes out of the blood stream. Or, Hypothyroidism is due to inadequate production of T4 (raw material) in the thyroid gland, and Wilson’s Temperature Syndrome is due to inadequate production of T3 (active hormone) in the tissues.

Low Thyroid Symptoms
Body Temperatures Thyroid Blood Tests
Wilson’s Thyroid Syndrome


Just because people have low body temperatures doesn’t mean they have hypothyroidism, because they may have normal thyroid blood tests, and Wilson’s Temperature Syndrome. This explains why people can still have classic low thyroid symptoms, normal thyroid blood tests, and still respond beautifully to the right kind of thyroid medicine given in the right way. This also explains how people with hypothyroidism can have their blood tests corrected with T4 and still feel poorly with classic symptoms.

They may be getting plenty of T4 but they may not be processing it properly. In other words, they may be suffering from Wilson’s Temperature Syndrome even though their hypothyroidism has been corrected. For decades, doctors have assumed that the T4 medicine they give patients to normalize their blood tests will be adequately converted to T3 in the tissues. There is no scientific basis for this assumption. The fact that patients frequently respond so dramatically and unequivocally to proper T3 therapy clearly suggests that this assumption is not only unfounded, but also incorrect.