The steps of diagnosis are essentially,

  1. Does the patient’s story sound typical of Wilson’s Temperature Syndrome?
  2. Is there any other great explanation for the patient’s complaints?
  3. Is there any reason the patient shouldn’t try the treatment for Wilson’s Temperature Syndrome?
  4. Try the T3 therapy protocol for Wilsons Temperature Syndrome and see how well it works.


Wilson’s Temperature Syndrome is largely a diagnosis of exclusion and is best identified with a therapeutic trial. What does that mean? It means that there are several identifiable medical conditions that can cause symptoms similar to Wilson’s Temperature Syndrome that can be easily ruled out or excluded by a qualified medical professional through tests. A “therapeutic trial” is a medical phrase that means “trying a treatment on a patient to see how well it works.” Therapeutic trials are especially helpful in establishing the diagnosis of conditions that are not easily identified with tests. The thinking is that if a patient responds to the treatment, there’s a good chance s/he has the condition. Sometimes doctors need to try treatments for different problems to see what works. Doctors recognize and are comfortable with these terms, and the treatment of Wilson’s Temperature Syndrome is “standard of care” medicine.

Does the patient’s story sound typical of Wilson’s Temperature Syndrome?

The best overall description of Wilsons Temperature Syndrome, how it comes on, and its typical manifestations in patients’ lives, can be found in the patient book, Wilson’s Temperature Syndrome — A Reversible Thyroid Problem. For a list of Wilsons Temperature Syndrome symptoms please see the sidebar to the right.

To recap,

  • The symptoms of Wilsons Temperature Syndrome are classic for low thyroid problems.
  • When the symptoms come on together they are more likely to be related.
  • The symptoms often persist even after the stress has passed.
  • Wilson’s Temperature Syndrome is characterized by body temperatures that average below 98.6 measured orally, typically below 97.8.
  • Wilsons Temperature Syndromeis 4 times more common in women than men.
  • Wilsons Temperature Syndromeappears to be more common in certain nationalities (especially those whose ancestors survived famine) such as American Indian, Irish, Scot, Welsh, Russian, etc.
  • For a complete description of the syndrome, please see the book, “Wilson’s Temperature Syndrome–A Reversible Thyroid Problem”.

Is there any other great explanation for the patient’s complaints?

Before starting patients on T3 therapy for Wilson’s Temperature Syndrome, it’s a good idea to make sure they don’t have any obvious and undiagnosed kidney or liver disease, anemia, leukemia, diabetes, and other problems that could explain some of the patients’ complaints. This can be accomplished with standard routine blood tests such as a multichemistry blood test or panel and a complete blood count (CBC). Depending on the laboratory, these tests may run about $42 combined.

Other causes of low thyroid symptoms such as primary and secondary hypothyroidism should also be ruled out. This can be accomplished by routine T4 and TSH tests. For an explanation of why Wilson’s Temperature Syndrome is undiagnosable with thyroid blood tests click here.

Wilson’s Temperature Syndrome is not the only possible explanation of all the symptoms it can cause, but it is one of the most treatable and “curable”. Curable is in quotes here because although Wilsons Temperature Syndrome can be corrected, it can possibly recur. Wilsons Temperature Syndrome can be thought of as a coping mechanism gone amuck. As long as that coping mechanism is there (which it will be) it can become unbalanced again.

Is there any reason the patient shouldn’t try the treatment for Wilson’s Temperature Syndrome?

Before patients try T3 therapy for Wilsons Temperature Syndrome it’s good to try and rule out obvious problems that could be made worse with T3 therapy such as an underlying heart condition or Addison’s disease. This can be accomplished with a history and physical, EKG, and review of the multichemistry test mentioned above.

Try the T3 therapy protocol for Wilsons Temperature Syndrome and see how well it works.

If the symptoms go away with treatment and the symptoms remain improved even after the treatment’s been discontinued, then the patient had Wilson’s Temperature Syndrome.

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