The body fights infection through the immune system. The immune system relies heavily on the action of enzymes for its function. Because of MED, the function of the immune system can decrease leading to more frequent, more severe, and longer lasting skin infections. Of course, acne is a well known symptom of DTSF. Acne is frequently a disease of adolescence and early teen years and is usually outgrown. When a person develops acne later in life after a major stress together with other symptoms of Wilson’s Temperature Syndrome, presenting in a way that is characteristic of other Wilson’s Temperature Syndrome symptoms, and when it resolves with the WT3 protocol, it is easy to see how acne can be related to Wilson’s Temperature Syndrome . Wilson’s Temperature Syndrome patients frequently say with regard to their acne problems: “I’m too old for this.” Of course, Wilson’s Temperature Syndrome can occur at any age, and body temperature patterns should be considered in any patient who is complaining of acne. Acne is frequently treated with antibiotics such as tetracycline, long term. One Wilson’s Temperature Syndrome sufferer had been less than perfectly controlled on four years of daily tetracycline therapy for her acne. With the WT3 protocol her acne resolved and she was able to wean off the tetracycline enjoying a persistent improvement in her acne even without tetracycline therapy.