Constipation is an extremely common associated symptom. Multiple Enzyme Dysfunction caused by low body temperature patterns can result in the slowing down of the gastrointestinal tract. This may lead to less frequent bowel movements, constipation, bloating, gas, abdominal cramping, irritable bowel syndrome/spastic colon, and indeed diarrhea. So decreased bowel motility can lead to constipation or maldigestion of food, and gaseous bloating leading to spastic contraction of the colon and diarrhea. As mentioned previously, these symptoms can respond remarkably well to proper liothyronine treatment, even when many other approaches have failed.