Patients with DTSF often find their symptoms to be improved with vitamin supplementation and these patients can often be quite knowledgeable on vitamins. Although they sometimes feel much better with vitamin therapy, they do not always return completely back to normal; nor do their improvements generally persist after vitamin therapy had been discontinued. These patients will frequently respond better to treating the underlying problem with proper thyroid hormone treatment. It may be that Wilson’s Temperature Syndrome affects intestinal absorption or body utilization of vitamins, so supplementation with vitamins is often quite helpful. However, after body temperature patterns have been normalized the patients’ symptoms of fatigue, depression, dry skin, dry hair, brittle nails, etc., frequently remain improved even after vitamin therapy and thyroid hormone therapy have been weaned.